Bupropion (Zyban) is an oral prescribed medicine that aids individuals to stop smoking cigarettes by decreasing hungers and removing some of the drawback signs. Bupropion hydrochloride extended release (SR) Images. What does Bupropion hydrochloride extended release (SR) look like? Note: Multiple pictures are displayed for those medicines available in different strengths, marketed under different brand names and for medicines manufactured by different pharmaceutical companies. Indications, dose, contra-indications, side-effects, interactions, cautions, warnings and other safety information for BUPROPION HYDROCHLORIDE. Each tablet contains bupropion hydrochloride 150 mg. For the full list of excipients, see section 6.1. Bupropion, sold under the brand names Wellbutrin and Zyban among others, is a medication primarily used to treat major depressive disorder and to support stopping smoking. It is an effective antidepressant on its own, but is also used as an add-on medication in cases of incomplete response to first-line SSRI antidepressants. Wellbutrin XL (bupropion hydrochloride extended-release) is an antidepressant used to treat major depressive disorder and seasonal affective disorder. [10-10-2013] FDA is providing an update on its request for studies to assess the bioequivalence of marketed bupropion hydrochloride (HCl) extended-release (ER) 300 mg tablets. DESCRIPTION. WELLBUTRIN XL® (bupropion hydrochloride), an antidepressant of the aminoketone class, is chemically unrelated to tricyclic, tetracyclic, selective serotonin reuptake inhibitor, or other known antidepressant agents. Contains Nonbinding Recommendations Draft Guidance on Bupropion Hydrochloride This draft guidance, once finalized, will represent the Food and Drug Administration's (FDA's) Bupropion/naltrexone is a combination drug used for weight loss in those that are either obese or overweight with some weight-related illnesses. It combines low doses of bupropion and naltrexone.